» Cayuse IRB

Submitting for IRB Review

The Chapman University Institutional Review Board (IRB) uses Cayuse IRB for submission and review of human subject research studies in accordance with institutional, federal, ethical, and regulatory standardsCayuse IRB is an easy-to-use, electronic system for preparing, submitting, and reviewing studies for IRB approval. All information is stored in the online Cayuse IRB system and can be accessed securely from any location. Multiple users can simultaneously view and access study documents. Additionally, study submissions can smoothly proceed from study creation to IRB approval, as users receive electronic notifications whenever they need to complete required tasks.

*Cayuse IRB runs on Internet Explorer 9 or higher, Mozilla Firefox, Google Chrome, or Apple Safari.


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+ - Authentication

Authentication is needed for investigators who have never submitted for IRB review or are receiving the message, "We're sorry. This account has been disabled on the Cayuse424 system,"upon login. To obtain access in Cayuse IRB, investigators need to request authentication in Cayuse IRB and email the following information to the IRB at irb@chapman.edu:

  • First and Last Name
  • Chapman email address (e.g. NAME100@mail.chapman.edu)
  • Status (faculty, staff, student, unaffiliated, etc., as appropriate)
  • Chapman University College and Department

Investigators can log into Cayuse IRB after their information is added and after Cayuse IRB completes its nightly sync process.

  • For student-directed studies, a list of student names and their above information must be submitted to the IRB
  • Authentication is not required for studies that include student research assistants who will be engaged in but who will not direct the study. Student research assistant names can be listed in Section 2 Personnel under "Other Chapman Researchers (Investigators)," along with others engaged in the research. 

If your information was incorrectly entered, you can correct your information by emailing the IRB at irb@chapman.edu.

+ - Instructions

+ - Submission Requirements

Below is a list of items that should be ready before starting a Cayuse IRB submission.
  • Study materials saved as separate documents (e.g., informed consent forms, letters of support from study sites, recruitment documents, survey questions, interview questions)
  • Copies of CITI completion certificates/reports from each member of the research team
  • All users "authenticated" in Cayuse IRB
    • See the Authentication tab for more information.

+ - Submission Types

Initial

This is the first submission that you create when you enter a new study in the system. The initial submission describes the research you intend to do and the methodology you intend to use. The initial submission must be approved before any research can begin.

Withdrawal

A withdrawal submission notifies the Integrity Office that you no longer wish to submit your initial submission and want to withdraw the study. Withdrawn studies are marked as finalized and can no longer be modified. You may create a withdrawal submission at any point once an initial submission has been created, until it has been approved. If the initial submission has been approved, you must create a closure submission in order to close the study if you no longer wish to conduct the research.

Legacy 

Used for studies imported from previous systems. The legacy submission replaces the initial submission for imported studies. Once the legacy submission is finalized, you can create additional submissions such as modifications, renewals, etc. 

Modification

If you wish to change any of the details of the study after it has been approved, you must submit a modification which must be approved before you can proceed with the changes. Modifications will only be available after initial approval is issued.  Modifications will be linked with the initial application and you will make revisions to the initial application based on the modifications you are requesting.

Renewal

When a study is nearing its expiration date, you must submit a renewal request in order to continue with the research. Expiration notices will be emailed from Cayuse.  Renewals, like modifications, will only be available after initial approval is issued.

Incident

You must submit an incident report to inform the Integrity Office of any adverse incidents, as required by your institution. Incident reports may be submitted at any time after a study has been approved, including after it has been closed. More than one incident report may be created for a given study, as needed.

Closure

A closure submission indicates that the research is complete and will not be continuing. Closed studies are marked as finalized and can no longer be modified.