» Post Doc & Guest Researchers

no photo available for Farideh Amirrad, M.D, Ph.D

Farideh Amirrad, M.D, Ph.D

Post Doctoral Fellow
photo of Ayan Barui, Ph.D.

Ayan Kumar Barui, Ph.D.

Post Doctoral Fellow
(949) 686-8602
Dr. Ayan Kumar Barui joined Chapman University School of Pharmacy in November 2021 as a Postdoctoral Fellow. Prior to joining Chapman University, Dr. Barui worked as Associate Principal Scientist in Patanjali Research Foundation, Haridwar, India (August 2020 – Decmber 2020) and Postdoctoral Research Associate in Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea (January 2018 – March 2020). He received his Ph.D. degree in Nanomedicine from CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad, India and Academy of Scientific and Innovative Research (AcSIR), New Delhi, India in June 2017. He is the recipient of the prestigious & competitive CSIR-UGC NET Junior Research Fellowship and Senior Research Fellowship from Govt. of India to pursue his Ph.D. degree. Dr. Barui is a research professional with 8+ years of total experience which comprises of 5+ years in PhD research and 3+ years in post – Ph.D. research (postdoctoral and industrial experience) with an expertise in leading research and development in the field of Chemistry and Biotechnology through effectively managing collaborative Nanomedicine projects (therapeutics for vascular diseases, cancers, neurodegenerative diseases, wounds as well as bio-imaging). He demonstrated an excellence in leading activities pertaining to laboratory management, mentoring young researchers, manuscript writing, preparation of research grant application and conference presentation as evidenced by more than 40 peer – reviewed international publications (research article, review, editorial and book chapter) and several international conference awards during doctoral and postdoctoral research journey. Dr. Barui is also recognized as an invited reviewer for various international journals including Acta Biomaterialia, Nanoscale, Materials Science and Engineering C, Biomaterials Science, Journal of Materials Chemistry B, Colloids and Surfaces B: Biointerfaces, RSC Advances and others, followed by the admission as a member (MRSC) of the prestigious Royal Society of Chemistry (RSC), UK. His current research focuses on understanding the underlying causes of ciliopathies and development of their treatment strategies using nanoparticles – based targeted drug delivery systems.
photo of Isabella  Cattani-Cavalieri, Ph.D.

Isabella Cattani-Cavalieri, Ph.D.

Postdoctoral Fellow
Dr. Isabella Cattani-Cavalieri joined the Chapman University School of Pharmacy as a Postdoctoral Fellow in July 2021. She received dual Ph.D. degrees in the Department of Molecular Pharmacology at University of Groningen, The Netherlands and in the Department of Morphological Sciences at Federal University of Rio de Janeiro, Brazil. The project of her Ph.D. investigated the role of air pollution and lung effects in inflammation and oxidative stress, and, more specifically, the impact on cAMP signaling and mitochondrial function. Dr. Cavalieri is investigating cAMP signaling compartmentation in airway smooth muscle and epithelial cells in the laboratory of Dr. Rennolds Ostrom.
no photo available for Devaraj Chandrashekar, Ph.D.

Devaraj Chandrashekar, Ph.D.

Postdoctoral Fellow
Dr. Devaraj Chandrashekar joined Chapman University School of Pharmacy as a Postdoctoral Fellow in June-2018. He received his Ph.D. in Pharmaceutical Sciences from Jawaharlal Nehru Technological University Hyderabad (JNTUH), India. He was the recipient of the prestigious & competitive post-graduate fellowship from All India Council of Technical Education (AICTE), New Delhi for his MS program. Dr. Chandrashekar has authored ~25 publications in various peer reviewed journals. Previously in the Chapman School of Pharmacy, he was associated with Dr. Mehvar’s research group where he worked on the development and optimization of drug metabolism studies and the characterization of cytochrome P-450 enzyme activities in subcellular fractions of various tissues like liver, kidney, and brain of rats by LC-MS/MS. During that time, he also focused on animal model development of acute on chronic liver disease and its treatment. Dr. Chandrashekar joined Dr. Sumbria’s research group in June 2021 and is currently working to characterize the effect of alcoholic-liver injury on neurovascular and neuronal-degeneration and its impact on the pathology of Alzheimer’s disease. Dr. Chandrashekar technical expertise lies in isolation, characterization, and structural elucidation of phytochemical constituents using various analytical techniques and evaluating their biological activity (invitro & in-vivo) for various pharmacological actions, in-vitro & in-vivo ADME screening, including high-throughput techniques in pharmacokinetics, bioanalysis, pharmacokinetic profiling across the species, and diseased state pharmacokinetic evaluation using suitable animal models.
no photo available for Rudy Chang, Ph.D.

Rudy Chang, Ph.D.

Postdoctoral Fellow
Rudy Chang joined the Chapman University School of Pharmacy as a Research Specialist in Dr. Sumbria’s research group in February 2021. His research focuses on Alzheimer’s Disease therapeutic development and the RBC-blood-brain barrier interaction studies. Rudy did his undergraduate studies at California State University Long Beach (CSULB) and received his degree in Psychology with emphasis in Neuroscience, with published research on neurogenesis in the avian hippocampus. After receiving his bachelor’s degree, he earned certifications in stem cell culture and aseptic techniques at Pasadena City College (PCC), followed by a fellowship at the University of Southern California (USC) to focus on efficient neural stem cell differentiation. Rudy then shifted his focus to antibody-drug conjugates in vivo drug studies for Alzheimer’s Disease, and immune cell interactions with the blood-brain barrier at Keck Graduate Institute (KGI) under Dr. Sumbria, and now continues this work at Chapman. Rudy also has extensive experience in clinical EEG studies for Alzheimer’s and Parkinson’s Disease, novel drug testing on patient-derived xenografts, and relevant large scale cGMP stem cell manufacturing.
photo of Sandeep Lohan, Ph.D.

Sandeep Lohan, Ph.D.

Postdoctoral Fellow
Dr. Sandeep Lohan joined Chapman University School of Pharmacy as a Postdoctoral Fellow in April 2019. He received his Ph.D. in Pharmaceutical sciences from Jaypee University of Information Technology, India. Dr. Lohan is a medicinal chemist specialized in peptide chemistry. The research themes underpinning his interests are of a multidisciplinary nature and fall broadly under the umbrella of medicinal chemistry. After the completion of his master’s degree, he was awarded a government funded research fellowship and enrolled for a doctoral research program. During his doctoral research, he rationally designed and successfully synthesized a library of short abiotic lipopeptides through solid phase chemistry. In addition, with an objective to probe essential properties of native antimicrobial peptides (AMPs) into a small structural framework, he carried out the synthesis of small cationic peptidomimetics by backbone modification. As part of his doctoral research program, he gained extensive training on solid/solution phase synthesis, purification, and analytical characterization of peptides and peptidomimetics. Furthermore, he got hands-on experience of in-vitro assays on mammalian and bacterial cells as well as various microbiology and biophysical techniques. Following the award of the doctoral degree, Dr. Lohan joined Aurigene Discovery Technologies Limited as scientist in the peptide R&D division. During his industrial research tenure, he was actively involved in a couple of internal and external collaborative drug discovery programs. The major assignment was development of small peptidomimetic molecules as immunomodulators. While working in diverse research projects, he successfully troubleshoots many challenges encountered in the area synthesis as well as purification of target molecules. Overall, Dr. Lohan gained extensive experience of pre-clinical development of peptides for various therapeutic applications. Dr Lohan’s current research endeavor is aimed at the development of peptide-inspired orally bioavailable antibiotics for the treatment of infectious diseases caused by the multi-drug resistant microbial pathogens. In this pursuit, he developed a library of macrocyclic peptides composed of unnatural amino acids with diverse side chain functionalities. As part of another research project, in collaboration with a USA based Biopharmaceutical Company, he is working on the development of peptide-based transfection agent. Dr. Lohan thoroughly enjoy research activities at various academic and industrial levels and always like to work in an environment where multiple tools are used for studying a problem of interest.
no photo available for Francisco Nunez, Ph.D.

Francisco Nunez, Ph.D.

Research Associate
Dr. Nunez received both his Master’s and PhD degrees from Chapman University, where he studied on the organization of cAMP signaling microdomains in lipid raft and non-raft regions in the plasma membrane and how these compartments generate unique cAMP signals that elicit specific responses. In one publication, he examined the role of long-term exposure of human lung fibroblast to cAMP-elevating agents and its implications in idiopathic pulmonary fibrosis. Results from the study revealed that the prostaglandin E receptor 2 (EP2) was desensitized by a 24-hour treatment with ONO-AE-259, which resulted in upregulated phosphodiesterase 4 (PDE4) activity. His recent studies focused on the non-genomic signaling elicited by glucocorticoids and whether this signaling pathway can be leveraged as a novel therapeutic treatment for asthma. I found that glucocorticoids stimulate cAMP production through a Gs-coupled GPCR in mammalians cells and this non-genomic pathway contributes to one third of its overall genomic effects.
photo of Mamunur  Rashid, Ph.D.

Mamunur Rashid, Ph.D.

Postdoctoral Fellow
Dr. Mamunur Rashid joined Chapman University School of Pharmacy in March 2021 as a Postdoctoral Fellow in the laboratory of Dr. Reza Mehvar. He received his Bachelor's degree (B.Sc.) in Biochemistry (2009-2012) and Master's degree (M.Sc.) in Biotechnology (2012-2014) from the Aligarh Muslim University, India. During post-graduation, he qualified for UGC-NET-JRF exam in biological sciences and received a fellowship for perusing Ph.D. studies. He earned his Ph.D. in Biological Sciences (Pharmacokinetics & Pharmaceutics; 2015-2020) from Jawaharlal Nehru University while working at the CSIR-Central Drug Research Institute, India. Dr. Rashid's work is focused on the preclinical pharmacokinetics of new chemical entities and natural products (bioavailability, dose-proportionality, species variability, allometric scaling) to inform the clinical studies to address the impact of pharmacokinetics at early drug discovery. His research helps to decipher the molecular mechanism of ADME/disposition and interaction of new molecules with drug metabolizing enzymes based on metabolic stability, formation of reactive metabolites, mass fragmentation, and metabolite identification, enzyme kinetics, drug transport and permeability across biological barriers. Dr. Rashid has developed advanced skills in bioanalysis in different biological matrices (blood, plasma, serum, tissue homogenates, feces and urine) using high-end analytical instruments like UPLC (Nexara and Scimadzu), LC-MS/MS (QTRAP 5500, QTRAP 4000 and API 4000). Along with bioanalytical tools and techniques, he is also experienced in gene and protein biology techniques, such as isolation of DNA and RNA from mammalian cells and tissue samples, PCR, qPCR, Western Blot and Immunoassays. His research interests include: pharmacokinetics, drug development, drug-drug interaction, and kinetics of cytochrome P450-mediated drug metabolism. Current Research: Understanding consequences and therapy of liver diseases.
photo of Young Woo Nam, Ph.D.

Young Woo Nam, Ph.D.

Postdoctoral Fellow
(714) 516-5495
Dr. Young Woo Nam joined the Chapman University School of Pharmacy as a Postdoctoral Fellow in November 2015. He received his Ph.D. in Department of Biotechnology at University of Tokyo, Japan. He studied three-dimensional structures of Glycoside Hydrolases (GHs) for understanding cellular metabolisms and determined two novel crystal structures. One of his work was published in Journal of Biological Chemistry (2015).
Dr. Nam is a structural biologist specializing in blending computational and experimental approaches to elucidate the molecular structure of proteins utilizing X-ray diffraction, computational biology image processing, bioinformatics and structural prediction. He is interested in protein conformational changes, protein-ligand interactions and structure-based drug design of small-conductance K+ channels (SK channels). Currently Dr. Nam researches with Dr. Zhang on the pharmacological modulation of KCa2/3 channels by small molecule drugs and structure based drug discovery for SK channels.
no photo available for Joshua Yang, Ph.D.

Joshua Yang, Ph.D.

Research Associate
no photo available for Jianwei Zheng, Ph.D.

Jianwei Zheng, Ph.D.

Research Associate