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School of Pharmacy

» Center for Targeted Drug Delivery

Drug synthesis process chart.

The mission of the Center for Targeted Drug Delivery (CTDD) is to design, develop, and evaluate novel approaches for targeted delivery of therapeutic agents. Our vision for the research conducted by our members is to improve the efficacy and safety of therapeutic agencies through innovative technologies.


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+ - Partnership Interest Form

The Center for Targeted Drug Delivery (CTDD) is seeking academic, industry and international partners for collaboration in our dynamic, innovative research. 

For more information on this exciting opportunity with Chapman's CTTD, please fill out this form »

Structural Biology Research Center  (SBRC)

The Structural Biology Research Center (SBRC) is housed by the Chapman University School of Pharmacy (CUSP) in the Harry and Diane Rinker Health Science Campus, Irvine. The center offers expertise and access to the cutting-edge instrumentation for biomolecular structural analysis and drug development, including x-ray crystallography, NMR spectroscopy, and protein-ligand interaction analysis.

Our mission at SBRC is to advance structure-based drug design and development by integration of structural and biophysical techniques for the characterization of structure and function of biomolecules and macromolecular complexes. To accomplish this mission, we aim to develop collaborations and partnerships with other academic institutions as well as Biotech and pharmaceutical companies. 

Center Activities: 

SBRC provides training, access to the equipment, and any needed assistance in sample preparation, as well as X-ray diffraction, NMR, and SPR data collection and analysis.

SBRC Members:

  • Dr. Simin Rahighi - X-ray Crystallography
  • Dr. Innokentiy Maslennikov - NMR Spectroscopy
  • Dr. Miao Zhang - X-ray Crystallography
  • Dr. Gennady Verkhivker - Computational Biology

Equipment


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+ - X-ray Crystallography

Mosquito LCP EquipmentMosquito Crystallization Robot (TTP Labtech. Inc)

  • High-throughput crystallization of biomacromolecules (soluble and membrane proteins, peptides)

 

 

 

MetaljetD8 Venture Liquid Gallium Metaljet (Bruker)

  • X-ray diffraction data collection
  • X-ray diffraction data analysis and structure determination

 

 

Stereo Microscope

Axiocam Erc

+ - Nuclear Magnetic Resonance (NMR)

Axiocam ErcAvance III HD 400 MHz (Bruker)

  • Solution NMR spectroscopy data collection (1H, 13C, 15N, 19F, 31P, etc.)
  • Small Molecule/Protein Characterization
  • Label-free detection of ligand-target interactions

+ - Protein-Ligand Interaction Assay

Biacore S200 Machine

Biacore S200 (GE Healthcare)

  • Surface Plasmon Resonance (SPR)
  • Label-free detection of protein-protein or protein-ligand interactions

+ - SBRC Pricing

For information regarding SBRC pricing, please click here to learn more.