» Dr. Aftab Ahmed
Associate Professor, Research Faculty and Core Laboratory Manager

School of Pharmacy
Dr. Aftab Ahmed
Office Location:
Rinker Health Science Campus Bldg. 9501 #206
Phone:
714-516-5465
Email:
Education
University of Karachi, Bachelor of Science
University of Karachi, Master of Science
University of Karachi, Ph.D.
Biography

Dr. Ahmed earned his Ph.D. degree in protein chemistry from HEJ Research Institute of Chemistry, University of Karachi, Pakistan in 1989. He completed a part of his Ph.D. thesis at the Department of Protein Chemistry, Max-Plank Institute of Biochemistry, Munich, Germany. After graduation, he rejoined Max-Planck Institute in 1988 as a postdoctoral fellow and continued his research work on the primary structure of Carnivore hemoglobin. He joined National Cancer Institute (NCI), Frederick, Maryland as a postdoctoral fellow in 1989 and worked on the characterization of retroviral proteins from HTLV-1 and BLV retroviruses. He joined as postgraduate researcher to work on the characterization of human fibrinogen at University of California Irvine 1992, and later established a Biomedical Sequencing and Synthesis Core Facility. He also worked on peptide synthesis at Harbor UCLA Medical Center. Ahmed also has industrial experience, working in biotechnology companies. He joined as a protein chemist at CytoTherapeutics Inc., Lincoln, Rhode Island in 1996. Later he joined as a Staff Scientist, Biochemistry R&D in a tissue engineering company, Organogenesis Inc, Canton, Massachusetts in 1998. Ahmed moved to academia and joined as a Coordinator and established a multi-million dollar Centralized Research Core Facility at the University of Rhode Island (URI) in June 2003, supported through IDeA Network of Biomedical Research Excellence Program, NIH. He became a Research Assistant professor at URI in May 2008 and is involved in teaching graduate and undergraduate courses at URI. He also participates in undergraduate network institutions in the RI-INBRE program. He is currently an adjunct faculty member at the International Center for Chemical and Biological Sciences (ICCBS), University of Karachi, Pakistan. He is conducting collaborative research projects related to bioactive proteins and peptides from various spices used as folk medicine in Pakistan, as well as the characterization of hemoglobin from snake Leaf-Nosed Viper. Dr. Ahmed has authored 24 peer-reviewed publications and 15 meeting abstracts.

Research Interests

Dr. Ahmed’s research interests include protein purification, characterization, and amino acid sequencing. (1) Primary structure of hemoglobin to understand inter-species relationship at molecular level. (2) Proteins and peptides profiling of plants based in folk medicine from Pakistan. He is an author of 24 peer-reviewed publications, and 15 meeting abstracts.

Recent Creative, Scholarly Work and Publications
Munir, I., S. Ajmal, M.R. Shah, A. Ahmed, A. Hameed and S.A. Ali. 2017. Protein drug nano-conjugates: Finding the alternative proteins as drug carrier. Int. J. Biol. Macromolecules. 101: 131-145
Waheed, H., H. Freedman, S.F. Moin, S. Zarina and A. Ahmed. 2016. The primary structure of ßI chains of hemoglobin from snake Sindhi krait (Bungarus sindanus sindanus). Protein J. 35: 193-201.
Atta, A.; Amber, A.; Hashim, Z.; Ahmed, A.; Zarina, S. Lactate Dehydrogenase like crystalline: A potential protective shield for Indian spiny-tailed lizard (Uromastix hardwickii) lens against environmental stress. Protein J. 2014, 33:128- 134.
Yao, L.; Danniels, S.J.; Moshnikova, A.; Kunznetsov, S.; Ahmed, A.; Engelman, D.M.; Reshetnyak, Y.K.; Andreev, O.A. pHLIP peptide targets nano-gold particles to tumors. PNAS, 2013, 110 (2) 465-470.
Kalkunte, S.; Neubeck, S.; Norris, W.E.; Cheng, S.; Kostadinov, S.; Hoang, D.V.; Ahmed, A.; Von Eggeling, F.; Shaikh, Z.; Padbury, J.F.; Berg, G.; Markert, U.; Sharma, S. Transthyretin Is Dysregulated in Preeclampsia, and its native form prevents the onset of disease in a preclinical Mouse model. The American J. Pathology 2013, 183(5): 1425-1436
Guo, L.; Panderi, I.; Yan, D.D.;Szulak, K.; Li, Y.; Chen, Y.; Ma, H.; Niesen, D.B.; Seeram, N.; Ahmed, A.; Yan, B.; Pantazatos, D.; Lu, W. A comparative study of hollow copper sulfide nanoparticles and hollow gold nanospheres on degradability and toxicity. ACS Nano 2013, 7(10):8780-8793.
Musharraf, S.G.; Muhammad, S.; Siddiqui, A.J.; Haq, N.; Ahmed, A. Quantitative analysis of some important metals and metalloids in tobacco products by inductively coupled plasma-mass spectrometry (ICP-MS). Journal Chemistry Central Journal 2012, 6 (1), 56-68.